The Importance of Serum Procalcitonin in Diagnosis and Treatment of Serious Bacterial Infections and Sepsis
نویسندگان
چکیده
The clinical utility of serum procalcitonin (PCT) levels continues to evolve. PCT is regarded as a promising candidate marker for making a diagnosis and antibiotic stewardship in patients with systemic infections. The aim of this review is to summarize the current evidence for PCT in different infections and clinical settings, and to discuss the reliability of this marker when used with validated diagnostic algorithms.
منابع مشابه
Procalcitonin: A Reliable Marker for the Diagnosis of Neonatal Sepsis
Objective(s) In the last few years, serum procalcitonin has been proposed as an early marker of infections in neonates, with varying results. In this study, we aimed to investigate the value of procalcitonin, and C- reactive protein in establishing the diagnosis of neonatal sepsis. Materials and Methods Blood samples were collected at admission from 69 neonates with suspected infection (admi...
متن کاملارزش تشخیصی سطح سرمی پروکلسیتونین در افتراق مننژیت باکتریال از غیرباکتریال در کودکان یک ماهه تا 18 ساله مرکز طبی کودکان ، 83-1382
Background: Bacterial meningitis is a fatal disease with high mortality and morbidity that needs emergency management. But due to nonspecific signs and symptoms it;aposs diagnosis in children is difficult. Recently procalcitonin has been used for diagnosis of serious bacterial infections like bacterial meningitis. We conducted a prospective study in children for evaluation of procalcitonin in d...
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متن کاملپروکلسیتونین سرمی یک عامل پیش‌بینی‌‌کننده پاسخ به درمان در بیماران مبتلا به سپسیس باکتریال بستری در ICU
Background: Sepsis is one of the most important causes of mortality in severely ill ICU patients. At least, a part of high mortality rate in sepsis patients is due to less specific clinical symptoms for prompt diagnosis. Recently some studies report that serum levels of procalcitonin will increase in these patients but changes of serum levels following treatments is not known. This study was de...
متن کاملThe Evaluation of Serum Procalcitonin Levels in Neonatal Infections
Background Procalcitonin is known as one of the bacteremia and sepsis markers such as cytokines, interleukin and reactive proteins. This study was conducted to determine the procalcitonin levels in neonatal sepsis. Materials and Methods In a cross-sectional study, the serum procalcitonin levels in 50 term newborns with suspected sepsis was compared with 50 healthy newborns in Ghaem Hospital, Ma...
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